Critical Care A Day
Saturday March 6, 2021
Saturday March 6, 2021
Q: Name few non-orthopedic trauma causes of Fat Embolism Syndrome (FES)?
Answer: Although FES is usually associated with either accidental or surgical trauma to bones, there are few significant non-orthopedic trauma causes of FES. These include
- soft tissue injury
- burns
- liposuction and lipo-injection
- fat grafting
- cardiopulmonary resuscitation (mostly due to intraosseous access)
- cesarean section
- donor-related FES after lung transplantation
- osteomyelitis
Besides the above, there are also many completely non-traumatic clinical causes of FES.
- * pancreatitis
- * diabetes mellitus
- * prolonged steroid therapy
- * sickle cell hemoglobinopathies
- * fatty liver disease Lipid infusion
- * cyclosporine solvent
- * intravenous lipid emulsion therapy
- * intraoperative cell salvage
- * metastases from fatty tumors
#trauma
#surgical-critical-care
References:
1. Levine M, Skolnik AB, Ruha AM, et al. Complications following antidotal use of intravenous lipid emulsion therapy. J Med Toxicol 2014; 10:10.
2. Mendoza-Morales RC, Camberos-Nava EV, Luna-Rosas A, et al. A fatal case of systemic fat embolism resulting from gluteal injections of vitamin e for cosmetic enhancement. Forensic Sci Int 2016; 259:e1.
3. Jacob S, Courtwright A, El-Chemaly S, et al. Donor-acquired fat embolism syndrome after lung transplantation. Eur J Cardiothorac Surg 2016; 49:1344.
4. Schrufer-Poland T, Singh P, Jodicke C, et al. Nontraumatic Fat Embolism Found Following Maternal Death after Cesarean Delivery. AJP Rep 2015; 5:e1.