Q: All of the following electrolyte/lab abnormalities are part of 'Cairo-Bishop definition of laboratory' for tumor lysis syndrome except?
A) Uric acid B) Potassium C) Phosphorus D) Calcium E) Sodium
Cairo-Bishop laboratory definition is the easiest way to establish the diagnosis of tumor lysis syndrome. If two or more laboratory values of uric acid, potassium, phosphorus, and calcium change > 25% at presentation or seven days after cytotoxic therapy.
1. Cairo MS, Bishop M. Tumour lysis syndrome: new therapeutic strategies and classification. Br J Haematol 2004; 127:3.
2. Coiffier B, Altman A, Pui CH, et al. Guidelines for the management of pediatric and adult tumor lysis syndrome: an evidence-based review. J Clin Oncol 2008; 26:2767